Immunoadsorption

Immunoadsorption is a procedure that removes specific blood group antibodies from the blood. It is needed to remove the antibodies against pathogenic antibodies. The procedure generally takes about three to four hours. Immunoadsorption was developed in the 1990s as a method of extracorporeal removal of molecules from the blood, in particular molecules of the immune system. Different number of devices/columns exist on the market, each with a different active component to which the molecule of interest attaches, allowing for selectivity in the molecules of interest. Immunoadsorption may be used as an alternative to plasma exchange in certain conditions. Evidence of benefit is lacking in those with kidney problems. Concerns include that it is expensive. Blood first passes to plasma filter. Plasma then passes on to immunoadsorption column before returning to patient.